SURFACE FUNCTIONALIZATION HAS BEEN WIDELY USED TO PREVENT AGGREGATION OR AGGLOMERATION OF RAW CNTS, AND CHANGES IN SURFACE CHEMISTRY ON CNTS MAY BE IMPORTANT AND RELEVANT FOR HEALTH EFFECTS.CARBON NANOTUBE-NATURAL BIOPOLYMER NANOVECTORS HAVE IMPORTANT POTENTIAL APPLICATIONS IN DELIVERY SYSTEM FOR DRUGS AND BIOMOLECULES. IN THIS WORK, THE USE OF MULTI-WALL CNTS AS NANOCARRIERS FOR DRUG LOADING AND CONTROLLED RELEASE IS DEMONSTRATED. WE PRESENT THE SYNTHESIS OF DIFFERENT FUNCTIONALIZED MWCNT FOR USING AS ANTI-HIV CARRIER: A) CARBOXYL FUNCTIONALIZED CNT, B) AMIDE FUNCTIONALIZED CNT, C) CHITOSAN GRAFTED MULTIWALLED CARBON NANOTUBES COMPOSITE (CS-MWCNT) VIA COVALENT MODIFICATION OF MWCNT WITH CS, D) CNT-CS NANOPARTICLES BASED ON AN IONOTROPIC GELATION INTERACTION.IN ORDER TO EVALUATE THE POTENTIAL UTILIZATION OF MWCNT NANOHYBRIDS AS A DRUG CARRIES THE DRUG RELEASE WITH THE TENOFOVIR (HYDROPHILIC ANTI-RETROVIRAL DRUG) WERE INVESTIGATED. THE PREPARED NANOPARTICLES WERE CHARACTERIZEDBY FTIR SPECTROSCOPY. TGA WAS APPLIED TO STUDY THE THERMAL STABILITIES, AND SEM TO INVESTIGATE THE MORPHOLOGY.COMPARING TO CHEMICAL-FUNCTIONALIZED CNTS, POLYMER MODIFIED CNTS PROVIDE HIGHER BIOCOMPATIBILITY AND IN VITRO DRUG RELEASE STUDIES OF THE MWCNT-CS NPS INDICATED THAT THE CUMULATIVE RELEASE RATEOF THE TENOFOVIR FROM THE GRAFTING NANOPARTICLES REACHES A MAXIMUM (90%) AFTER ABOUT 120 H.

A BIOFUEL CELL IS AN ELECTROCHEMICAL DEVICE IN WHICH THE ENERGY STORED IN A FUEL, SUCH AS ETHANOL, IS CONVERTED TO ELECTRICAL ENERGY BY MEANS OF THE CATALYTIC ACTIVITY OF EITHER AN ENZYME OR A MICROORGANISM. BIOFUEL CELLS HAVE TRADITIONALLY SUFFERED FROM LOW POWER DENSITIES AND SHORT LIFETIMES DUE TO THE FRAGILITY OF THE BIO-CATALYST. UTILIZING A NOVEL IONIC LIQUID-CARBOXYLATED MULTIWALL CARBON NANOTUBE NANOCOMPOSITE FOR ALCOHOL DEHYDROGENASE ENZYME IMMOBILIZATION IN A BIOFUEL CELL RESULTS IN INCREASING THE ENZYME LIFETIME TO COMMERCIALLY VIABLE LEVELS.ADDITIONALLY, THIS METHOD PROVIDES SUFFICIENT PROTECTION TO DEVELOP A MEMBRANELESS BIOFUEL CELL, AN IMPORTANT STEP FOR COMMERCIALIZATION. PREVIOUSLY, IT HAS NOT BEEN POSSIBLE TO CREATE A MEMBRANELESS STYLE BIOFUEL CELL DUE TO THE DENATURING OF THE ENZYME THAT WOULD OCCUR AT THE HIGH TEMPERATURES EXPERIENCED DURING THE HEAT PRESSING STEP OF FABRICATION. A NANOCOMPOSITE CONSISTING OF IONIC LIQUID-CARBOXYLATED MULTIWALL CARBON NANOTUBE PROVIDES SUFFICIENT PROTECTION FOR THE ALCOHOL DEHYDROGENASE TO RETAIN THE ENZYME ACTIVITY AFTER EXPOSURE TO TEMPERATURES OF 40OC. THUS, A MEMBRANELESS BIOFUEL CELL WAS PREPARED. PRELIMINARY RESULTS OF THE BIOFUEL CELL REVEALED THE POWER DENSITY RANGING FROM 1.7 TO 10MW/CM2 AND THE OPEN CIRCUIT VOLTAGE FROM 0.599 TO 0.360 V.

HYDRAZINE (ALSO CALLED DIAZANE) (HZ) IS AN INORGANIC COMPOUND WITH THE FORMULA N2H4. HZ AND ITS DERIVATIVES HAVE BEEN RECOGNIZED AS POTENTIAL CARCINO-GENS. WHEN ABSORBED THROUGH SKIN THEY PRODUCE CAUSTIC-LIKEBURN, AFFECT BLOOD PRODUCTION AND ALSO CAUSE DAMAGES TO LIVERAND KIDNEY. THEREFORE DEVELOPMENT OF A SIMPLE AND SENSITIVE ANALYTICAL METHOD FOR THE DETERMINATION OF HZ IS NECESSARY FOR HUMAN HEALTH INSPECTIONS AND SAFETY ASSESSMENTS [1]. ELECTROCHEMICAL TECHNIQUES BECAUSE OF THEIR GOOD SENSITIVITY, SIMPLICITY, GOOD STABILITY AND LOW COST ARE THE GOOD CHOICE FOR DETERMINATION OF HZ [1]. IONIC LIQUIDS (ILS) HAVE ATTRACTED GREAT ATTENTION IN THE FIELD OF ELECTROANALYTICAL CHEMISTRY DUE TO THEIR EXCELLENT PROPERTIES SUCH AS HIGH ELECTRONIC CONDUCTIVITY, WIDE ELECTROCHEMICAL WINDOWS AND INHERENT CATALYTIC EFFECT AS NOT ONLY THE SOLVENT BUT ALSO THE MODIFIER [2]. CARBON NANOTUBES, BECAUSE OF THEIR UNIQUE PROPERTIES SUCH AS HIGH ELECTRICAL CONDUCTIVITY, HIGH SURFACE AREA, CHEMICAL STABILITY, AND SIGNIFICANT MECHANICAL STRENGTH HAVE ATTRACTED MUCH ATTENTION IN ELECTROCHEMISTRY. THEY CAN BE USED AS ELECTRODE MATERIALS TO PROMOTE ELECTRON TRANSFER REACTIONS IN ELECTROCHEMICAL DEVICES. ON THE OTHER HAND, FERROCENE AND ITS DERIVATIVES DUE TO THEIR GOOD STABILITY IN SOLUTION, RAPID RESPONSES TO MANY ELECTROACTIVE SUBSTANCES, INDEPENDENT PH, STABILITY IN BOTH OXIDIZED AND REDUCED FORMS, UNREACTIVITY WITH OXYGEN, REGENERATION AT LOW POTENTIAL AND HAVING FAST ELECTRON TRANSFER ARE THE MOST SUCCESSFUL MEDIATORS [3]. IN THE PRESENT WORK FERROCENE FUNCTIONALIZED IONIC LIQUID/ CARBON NANOTUBE NANOCOMPOSITE WAS USED FOR SURFACE MODIFICATION OF CARBON-CERAMIC ELECTRODE. THIS MODIFIED ELECTRODE WAS APPLIED FOR MEDIATORY DETERMINATION OF HYDRAZINE. UNDER THE OPTIMIZED OPERATIONAL PARAMETERS THE MODIFIED ELECTRODE BEHAVED LINEARLY TO HYDRAZINE CONCENTRATION IN THE RANGE OF 3×10-8-8×10-6 M BY HYDRODYNAMIC AMPEROMETRY TECHNIQUE. THE DETECTION LIMIT WAS 1.1×10-8 M. THE APPLICABILITY OF THIS TECHNIQUE IS FURTHER TESTED BY ANALYZING THE HYDRAZINE CONTENT IN BOILERS’ WATER SAMPLES CONTAINING DIFFERENT CONCENTRATIONS OF HYDRAZINE WITH APPRECIABLE RECOVERY VALUES.